Myb ELISA Kit for Mouse(Mus musculus) | EIAab.comMyb ELISA Kit for Mouse(Mus musculus)

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Myb (Gene name),

Transcriptional activator Myb (Protein name ), MYB_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Myb;

Protein name:

Transcriptional activator Myb;

Alternative:

Proto-oncogene c-Myb;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Binds to HIPK1 (By similarity). Interacts with HIPK2, MAF, MYBBP1A and NLK.

Function:

Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

636

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

636:

SGAWEPASCG | KTEDQMTASG | PARKYVNAFS | ARTLVM

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF09316

UniGene:

Mm.52109

String:

P06876

UniGene:

Mm.473872

SMR:

P06876

KEGG:

mmu:17863

Uniprot:

P06876

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ELISA Kit for Mouse Transcriptional activator Myb

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E1055m

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96T

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ELISA Kit for Mouse Transcriptional activator Myb

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E1055h

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96T

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ELISA Kit for Mouse Transcriptional activator Myb

Cat.:

E1055b

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MSDS:

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Packing:

96T

ELISA Kit for Mouse Transcriptional activator Myb

Cat.:

E1055c

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Packing:

96T

CLIA Kit for Mouse Transcriptional activator Myb

Cat.:

U1055c

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Packing:

96T

CLIA Kit for Mouse Transcriptional activator Myb

Cat.:

U1055h

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Mouse Transcriptional activator Myb

Cat.:

U1055b

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Transcriptional activator Myb

Cat.:

U1055m

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96T

Polyclonal Antibody for Mouse Transcriptional activator Myb

Cat.:

P1055Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Transcriptional activator Myb

Cat.:

P1055Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse Transcriptional activator Myb

Protein for Mouse Transcriptional activator Myb

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Murine myb protooncogene mRNA: cDNA sequence and evidence for 5' heterogeneity."
Bender T.P. , Kuehl W.M.
Proc. Natl. Acad. Sci. U.S.A.83:3204-3208(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
2.

"Nucleotide sequence of cDNA clones of the murine myb proto-oncogene."
Gonda T.J. , Gough N.M. , Dunn A.R. , de Blaquiere J.
EMBO J.4:2003-2008(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
3.

"Multiple c-myb transcript cap sites are variously utilized in cells of mouse haemopoietic origin."
Watson R.J. , Dyson P.J. , McMahon J.
EMBO J.6:1643-1651(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
4.

"Aberrant splicing events that are induced by proviral integration: implications for myb oncogene activation."
Rosson D. , Dugan D. , Reddy E.P.
Proc. Natl. Acad. Sci. U.S.A.84:3171-3175(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
5.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: FVB/N.
tissue: Mammary gland.
7.

"Structure and biological activity of the transcriptional initiation sequences of the murine c-myb oncogene."
Sobieszczuk P.W. , Gonda T.J. , Dunn A.R.
Nucleic Acids Res.17:9593-9611(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-47
8.

"Two modes of c-myb activation in virus-induced mouse myeloid tumors."
Shen-Ong G.L.C. , Morse H.C. III , Potter M. , Mushinski F.
Mol. Cell. Biol.6:380-392(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 72-636
9.

"Structural organization and nucleotide sequence of mouse c-myb oncogene: activation in ABPL tumors is due to viral integration in an intron which results in the deletion of the 5' coding sequences."
Lavu S. , Reddy E.P.
Nucleic Acids Res.14:5309-5320(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 72-401
10.

"Truncation of the c-myb gene by a retroviral integration in an interleukin 3-dependent myeloid leukemia cell line."
Weinstein Y. , Ihle J.N. , Lavu S. , Reddy P.E.
Proc. Natl. Acad. Sci. U.S.A.83:5010-5014(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 388-402
11.

"Activation of c-myb by carboxy-terminal truncation: relationship to transformation of murine haemopoietic cells in vitro."
Gonda T.J. , Buckmaster C. , Ramsay R.G.
EMBO J.8:1777-1783(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DOMAIN C-TERMINAL
12.

"Transformation by carboxyl-deleted Myb reflects increased transactivating capacity and disruption of a negative regulatory domain."
Hu Y. , Ramsay R.G. , Kanei-Ishii C. , Ishii S. , Gonda T.J.
Oncogene6:1549-1553(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NEGATIVE REGULATORY DOMAIN
13.

"Negative autoregulation of c-Myb activity by homodimer formation through the leucine zipper."
Nomura T. , Sakai N. , Sarai A. , Sudo T. , Kanei-Ishii C. , Ramsay R.G. , Favier D. , Gonda T.J. , Ishii S.
J. Biol. Chem.268:21914-21923(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DOMAIN LEUCINE-ZIPPER;NEGATIVE AUTOREGULATION
14.

"Molecular cloning reveals that the p160 Myb-binding protein is a novel, predominantly nucleolar protein which may play a role in transactivation by Myb."
Tavner F.J. , Simpson R. , Tashiro S. , Favier D. , Jenkins N.A. , Gilbert D.J. , Copeland N.G. , Macmillan E.M. , Lutwyche J. , Keough R.A. , Ishii S. , Gonda T.J.
Mol. Cell. Biol.18:989-1002(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH MYBBP1A1
15.

"c-Maf interacts with c-Myb to regulate transcription of an early myeloid gene during differentiation."
Hedge S.P. , Kumar A. , Kurschner C. , Shapiro L.H.
Mol. Cell. Biol.18:2729-2737(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH MAF
16.

"Wnt-1 signal induces phosphorylation and degradation of c-Myb protein via TAK1, HIPK2, and NLK."
Kanei-Ishii C. , Ninomiya-Tsuji J. , Tanikawa J. , Nomura T. , Ishitani T. , Kishida S. , Kokura K. , Kurahashi T. , Ichikawa-Iwata E. , Kim Y. , Matsumoto K. , Ishii S.
Genes Dev.18:816-829(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HIPK2 AND NLK
17.

"c-Maf interacts with c-Myb to down-regulate Bcl-2 expression and increase apoptosis in peripheral CD4 cells."
Peng S. , Lalani S. , Leavenworth J.W. , Ho I.-C. , Pauza M.E.
Eur. J. Immunol.37:2868-2880(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH MAF
18.

"Solution structure of a DNA-binding unit of Myb: a helix-turn-helix-related motif with conserved tryptophans forming a hydrophobic core."
Ogata K. , Hojo H. , Aimoto S. , Nakai T. , Nakamura H. , Sarai A. , Ishii S. , Nishimura Y.
Proc. Natl. Acad. Sci. U.S.A.89:6428-6432(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 142-193
19.

"Secondary structure of the DNA-binding domain of the c-Myb oncoprotein in solution. A multidimensional double and triple heteronuclear NMR study."
Jamin N. , Gabrielsen O.S. , Gilles N. , Lirsac P.-N. , Toma F.
Eur. J. Biochem.216:147-154(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 89-192
20.

"Comparison of the free and DNA-complexed forms of the DNA-binding domain from c-Myb."
Ogata K. , Morikawa S. , Nakamura H. , Hojo H. , Yoshimura S. , Zhang R. , Aimoto S. , Ametani Y. , Hirata Z. , Sarai A. , Ishii S. , Nishimura Y.
Nat. Struct. Biol.2:309-320(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 38-89; 90-141 AND 142-193
21.

"A small engineered protein lacks structural uniqueness by increasing the side-chain conformational entropy."
Furukawa K. , Oda M. , Nakamura H.
Proc. Natl. Acad. Sci. U.S.A.93:13583-13588(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 140-193
22.

"Mechanism of c-Myb-C/EBP beta cooperation from separated sites on a promoter."
Tahirov T.H. , Sato K. , Ichikawa-Iwata E. , Sasaki M. , Inoue-Bungo T. , Shiina M. , Kimura K. , Takata S. , Fujikawa A. , Morii H. , Kumasaka T. , Yamamoto M. , Ishii S. , Ogata K.
Cell108:57-70(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) OF 35-193 IN COMPLEX WITH HUMAN CEBPB

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